SpongeBob SquarePants premiered on Nickelodeon in 1999 and became an instant classic.
The Powerpuff Girls premiered on Cartoon Network in 1999 and became one of the most popular cartoons of the decade.
Batman Beyond premiered on Kids' WB in 1999 and continued the legacy of the Batman animated series from the 1990s.
Digimon Adventure premiered on Fox Kids in 1999 and helped to popularize the anime genre in the United States.
Johnny Bravo premiered on Cartoon Network in 1999 and featured a zany character who attempted to win the hearts of women with questionable tactics.
Family Guy premiered on Fox in 1999 but was canceled after only three seasons, before being revived in 2005.
Futurama premiered on Fox in 1999 and followed the adventures of a delivery boy who is cryogenically frozen and wakes up in the future.
Ed, Edd n Eddy premiered on Cartoon Network in 1999 and followed the misadventures of a group of young boys in a suburban cul-de-sac.
South Park continued to air in 1999 and caused controversy with its irreverent humor and satirical take on current events.
The Simpsons, which had been on the air since 1989, aired its tenth season in 1999 and continued to be a popular and influential animated sitcom.
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